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Homeostatic Dysregulation in Membrane Properties of Masticatory Motoneurons Compared with Oculomotor Neurons in a Mouse Model for Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative motoneuron disease with presently no cure. Motoneuron (MN) hyperexcitability is commonly observed in ALS and is suggested to be a precursor for excitotoxic cell death. However, it is unknown whether hyperexcitability also occurs...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Venugopal, Sharmila, Hsiao, Chie-Fang, Sonoda, Takuma, Wiedau-Pazos, Martina, Chandler, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293417/
https://ncbi.nlm.nih.gov/pubmed/25589764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1682-14.2015
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