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CD25(+)Bcl6(low) T follicular helper cells provide help to maturing B cells in germinal centers of human tonsil
The majority of CXCR5(+)PD-1(+)CD4(+) T follicular helper (Tfh) cells (>90%) are CD25(−)Bcl6(hi), while a small subpopulation (<10%) are CD25(+)Bcl6(low) but do not express FoxP3 and are not T regulatory cells. We purified T:B-cell conjugates from tonsil and found they were enriched for the CD...
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| Publié dans: | Eur J Immunol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293275/ https://ncbi.nlm.nih.gov/pubmed/25263533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444911 |
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