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CD25(+)Bcl6(low) T follicular helper cells provide help to maturing B cells in germinal centers of human tonsil

The majority of CXCR5(+)PD-1(+)CD4(+) T follicular helper (Tfh) cells (>90%) are CD25(−)Bcl6(hi), while a small subpopulation (<10%) are CD25(+)Bcl6(low) but do not express FoxP3 and are not T regulatory cells. We purified T:B-cell conjugates from tonsil and found they were enriched for the CD...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Eur J Immunol
Päätekijät: Li, Haishan, Pauza, C. David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293275/
https://ncbi.nlm.nih.gov/pubmed/25263533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444911
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