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Surface-templated hydrogel patterns prompt matrix-dependent migration of breast cancer cells towards chemokine-secreting cells

This paper describes a novel technique to fabricate spatially-defined cell-laden collagen hydrogels, using patterned, non-adhesive polyacrylamide-coated polydimethylsiloxane (PDMS) surfaces as a template. Precisely patterned embedded co-cultures of breast cancer cells and chemokine-producing cells g...

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Détails bibliographiques
Publié dans:Acta Biomater
Auteurs principaux: Kojima, Taisuke, Moraes, Christopher, Cavnar, Stephen P., Luker, Gary D., Takayama, Shuichi
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293228/
https://ncbi.nlm.nih.gov/pubmed/25463502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.11.033
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