Biosynthesis of Mycophenolic Acid: Purification and Characterization of S-Adenosyl-l-Methionine:Demethylmycophenolic Acid O-Methyltransferase

The final step in the biosynthesis of mycophenolic acid involves the transfer of a methyl group from S-adenosylmethionine to demethylmycophenolic acid. The enzyme, S-adenosylmethionine:demethylmycophenolic acid O-methyltransferase, was isolated from Penicillium stoloniferum and purified 2,700-fold b...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Muth, W. L., Nash, C. H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1975
Schlagworte:	Chemistry; Mechanisms of Action and Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/241289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.3.321
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