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Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones

During brain development the duration of miniature inhibitory postsynaptic currents (mIPSCs) mediated by GABA(A) receptors (GABA(A)Rs) progressively reduces, to accommodate the temporal demands required for precise network activity. Conventionally, this synaptic plasticity results from GABA(A)R subu...

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Pubblicato in:J Physiol
Autori principali: Brown, Adam R, Herd, Murray B, Belelli, Delia, Lambert, Jeremy J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293067/
https://ncbi.nlm.nih.gov/pubmed/25556800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.280263
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