Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones

During brain development the duration of miniature inhibitory postsynaptic currents (mIPSCs) mediated by GABA(A) receptors (GABA(A)Rs) progressively reduces, to accommodate the temporal demands required for precise network activity. Conventionally, this synaptic plasticity results from GABA(A)R subu...

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Bibliographic Details
Published in:J Physiol
Main Authors: Brown, Adam R, Herd, Murray B, Belelli, Delia, Lambert, Jeremy J
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
Subjects:
Neuroscience: Development/Plasticity/Repair
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293067/
https://ncbi.nlm.nih.gov/pubmed/25556800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.280263
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