Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis

INTRODUCTION: Genetic susceptibility to complex diseases has been intensively studied during the last decade, yet only signals with small effect have been found leaving open the possibility that subgroups within complex traits show stronger association signals. In rheumatoid arthritis (RA), autoanti...

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Publicado no:Arthritis Res Ther
Main Authors: Snir, Omri, Gomez-Cabrero, David, Montes, Ariana, Perez-Pampin, Eva, Gómez-Reino, Juan J, Seddighzadeh, Maria, Klich, Katharina U, Israelsson, Lena, Ding, Bo, Catrina, Anca I, Holmdahl, Rikard, Alfredsson, Lars, Klareskog, Lars, Tegnér, Jesper, Gonzalez, Antonio, Malmström, Vivianne, Padyukov, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292996/
https://ncbi.nlm.nih.gov/pubmed/25138370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0414-3
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