Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis

INTRODUCTION: Genetic susceptibility to complex diseases has been intensively studied during the last decade, yet only signals with small effect have been found leaving open the possibility that subgroups within complex traits show stronger association signals. In rheumatoid arthritis (RA), autoanti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Arthritis Res Ther
Main Authors: Snir, Omri, Gomez-Cabrero, David, Montes, Ariana, Perez-Pampin, Eva, Gómez-Reino, Juan J, Seddighzadeh, Maria, Klich, Katharina U, Israelsson, Lena, Ding, Bo, Catrina, Anca I, Holmdahl, Rikard, Alfredsson, Lars, Klareskog, Lars, Tegnér, Jesper, Gonzalez, Antonio, Malmström, Vivianne, Padyukov, Leonid
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292996/
https://ncbi.nlm.nih.gov/pubmed/25138370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0414-3
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