Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis

INTRODUCTION: Genetic susceptibility to complex diseases has been intensively studied during the last decade, yet only signals with small effect have been found leaving open the possibility that subgroups within complex traits show stronger association signals. In rheumatoid arthritis (RA), autoanti...

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Published in:Arthritis Res Ther
Main Authors: Snir, Omri, Gomez-Cabrero, David, Montes, Ariana, Perez-Pampin, Eva, Gómez-Reino, Juan J, Seddighzadeh, Maria, Klich, Katharina U, Israelsson, Lena, Ding, Bo, Catrina, Anca I, Holmdahl, Rikard, Alfredsson, Lars, Klareskog, Lars, Tegnér, Jesper, Gonzalez, Antonio, Malmström, Vivianne, Padyukov, Leonid
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292996/
https://ncbi.nlm.nih.gov/pubmed/25138370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0414-3
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