Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis

Gene-gene and gene-environment interactions are key features in the development of rheumatoid arthritis (RA) and other complex diseases. The aim of this study was to use and compare three different definitions of interaction between the two major genetic risk factors of RA—the HLA-DRB1 shared epitop...

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Main Authors: Källberg, Henrik, Padyukov, Leonid, Plenge, Robert M., Rönnelid, Johan, Gregersen, Peter K., van der Helm-van Mil, Annette H. M., Toes, Rene E. M., Huizinga, Tom W., Klareskog, Lars, Alfredsson, Lars
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852748/
https://ncbi.nlm.nih.gov/pubmed/17436241
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