The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling

Blood vessel stability is essential for embryonic development; in the adult, many diseases are associated with loss of vascular integrity. The ETS transcription factor ERG drives expression of VE-cadherin and controls junctional integrity. We show that constitutive endothelial deletion of ERG (Erg(c...

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Publicado en:Dev Cell
Main Authors: Birdsey, Graeme M., Shah, Aarti V., Dufton, Neil, Reynolds, Louise E., Osuna Almagro, Lourdes, Yang, Youwen, Aspalter, Irene M., Khan, Samia T., Mason, Justin C., Dejana, Elisabetta, Göttgens, Berthold, Hodivala-Dilke, Kairbaan, Gerhardt, Holger, Adams, Ralf H., Randi, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292982/
https://ncbi.nlm.nih.gov/pubmed/25584796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.11.016
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