Anti-nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist

BACKGROUND AND PURPOSE: The opioid receptor family comprises four structurally homologous but functionally distinct sub-groups, the μ (MOP), δ (DOP), κ (KOP) and nociceptin (NOP) receptors. As most opioid agonists are selective but not specific, a broad spectrum of behaviours due to activation of di...

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Publicat a:Br J Pharmacol
Autors principals: Taylor, A M W, Roberts, K W, Pradhan, A A, Akbari, H A, Walwyn, W, Lutfy, K, Carroll, F I, Cahill, C M, Evans, C J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2015
Matèries:
Themed Section: Opioids: New Pathways to Functional Selectivity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292979/
https://ncbi.nlm.nih.gov/pubmed/24923251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12810
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