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Dorsal hippocampal NMDA receptor blockade impairs extinction of naloxone-precipitated conditioned place aversion in acute morphine-treated rats by suppressing ERK and CREB phosphorylation in the basolateral amygdala

BACKGROUND AND PURPOSE: Substantial evidence shows that negative reinforcement resulting from the aversive affective consequences of opiate withdrawal may play a crucial role in drug relapse. Understanding the mechanisms underlying the loss (extinction) of conditioned aversion of drug withdrawal cou...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Br J Pharmacol
मुख्य लेखकों: Wang, Wei-Sheng, Chen, Zhong-Guo, Liu, Wen-Tao, Chi, Zhi-Qiang, He, Ling, Liu, Jing-Gen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Blackwell Publishing Ltd 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292962/
https://ncbi.nlm.nih.gov/pubmed/24597568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12671
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