A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells

Ovarian cancer is the second most common gynecological cancer and the five-year survival rate is only about 40%. High-grade serous carcinoma is the pre-dominant histotype associated with hereditary ovarian cancer and women with inherited mutations in BRCA1 have a lifetime risk of 40–60%. BRCA1 and i...

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Publicado en:Enliven Chall Cancer Detect Ther
Main Authors: Xu, Jingyao, Agyemang, Stephanie, Qin, Yunlong, Aysola, Kartik, Giles, Mercedes, Oprea, Gabriela, O’Regan, Ruth M, Partridge, Edward E, Harris-Hooker, Sandra, Rice, Valarie Montgomery, Reddy, E. Shyam P, Rao, Veena N
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292936/
https://ncbi.nlm.nih.gov/pubmed/25594072
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