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Naproxen Induces Type X Collagen Expression in Human Bone-Marrow-Derived Mesenchymal Stem Cells Through the Upregulation of 5-Lipoxygenase

Several studies have shown that type X collagen (COL X), a marker of late-stage chondrocyte hypertrophy, is expressed in mesenchymal stem cells (MSCs) from osteoarthritis (OA) patients. We recently found that Naproxen, but not other nonsteroidal anti-inflammatory drugs (NSAIDs) (Ibuprofen, Celebrex,...

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Publicat a:Tissue Eng Part A
Autors principals: Alaseem, Abdulrahman M., Madiraju, Padma, Aldebeyan, Sultan A., Noorwali, Hussain, Antoniou, John, Mwale, Fackson
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292866/
https://ncbi.nlm.nih.gov/pubmed/25091567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2014.0148
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