Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules

INTRODUCTION: We previously showed that type X collagen, a marker of late stage chondrocyte hypertrophy (associated with endochondral ossification), is constitutively expressed by mesenchymal stem cells (MSCs) from osteoarthritis patients and this may be related to Naproxen (Npx), a nonsteroidal ant...

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Publicat a:Arthritis Res Ther
Autors principals: Salem, Omar, Wang, Hong Tian, Alaseem, Abdulrahman M, Ciobanu, Ovidiu, Hadjab, Insaf, Gawri, Rahul, Antoniou, John, Mwale, Fackson
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223691/
https://ncbi.nlm.nih.gov/pubmed/25034046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4614
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