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Chimeric antigen receptor engineered T cells can eliminate brain tumors and initiate long-term protection against recurrence
CAR therapy has shown promise in treating cancer, but at the cost of unexpected toxicity against normal tissues, not predicted by preclinical testing. We are working to generate more physiologically relevant models for preclinical CAR toxicity testing, and in doing so, have discovered that CAR thera...
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Publicado no: | Oncoimmunology |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292711/ https://ncbi.nlm.nih.gov/pubmed/25610729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.944059 |
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