TGN exit of the cation-independent mannose 6-phosphate receptor does not require acid hydrolase binding

The cation-independent mannose 6-phosphate (Man-6-P) receptor (CI-MPR) binds newly synthesized, Man-6-P-containing lysosomal acid hydrolases in the trans-Golgi network (TGN) for clathrin-mediated transport to endosomes. It has remained unresolved, however, whether acid hydrolase binding is required...

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Bibliographic Details
Published in:Cell Logist
Main Authors: van Meel, Eline, Klumperman, Judith
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292573/
https://ncbi.nlm.nih.gov/pubmed/25610721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21592780.2014.954441
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