Identification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor

The 300 kDa cation-independent mannose 6-phosphate receptor (CI-MPR) plays an essential role in lysosome biogenesis by targeting ∼60 different phosphomannosyl-containing acid hydrolases to the lysosome. This type I membrane glycoprotein has a large extracellular region comprised of 15 homologous dom...

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Publicado en:Glycobiology
Autores principales: Olson, Linda J, Castonguay, Alicia C, Lasanajak, Yi, Peterson, Francis C, Cummings, Richard D, Smith, David F, Dahms, Nancy M
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410830/
https://ncbi.nlm.nih.gov/pubmed/25573276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwv001
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