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Incorporation of Double-Labeled l-Cystine and dl-Valine in Penicillin

l-[3,3′-(3)H]cystine was incorporated into penicillin with retention of one tritium. This result can be explained by β-lactam formation through ring closure between C3 of cysteine and NH of valine. No radioactivity of dl-[2,3-(3)H]valine was incorporated into penicillin. The loss of isotope at C2 oc...

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Detalles Bibliográficos
Main Authors: Adriaens, P., Vanderhaeghe, H., Meesschaert, B., Eyssen, H.
Formato: Artigo
Idioma:Inglês
Publicado: 1975
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC429252/
https://ncbi.nlm.nih.gov/pubmed/809001
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