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Incorporation of Double-Labeled l-Cystine and dl-Valine in Penicillin

l-[3,3′-(3)H]cystine was incorporated into penicillin with retention of one tritium. This result can be explained by β-lactam formation through ring closure between C3 of cysteine and NH of valine. No radioactivity of dl-[2,3-(3)H]valine was incorporated into penicillin. The loss of isotope at C2 oc...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Adriaens, P., Vanderhaeghe, H., Meesschaert, B., Eyssen, H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1975
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429252/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/809001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.1.15
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