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Incorporation of Double-Labeled l-Cystine and dl-Valine in Penicillin
l-[3,3′-(3)H]cystine was incorporated into penicillin with retention of one tritium. This result can be explained by β-lactam formation through ring closure between C3 of cysteine and NH of valine. No radioactivity of dl-[2,3-(3)H]valine was incorporated into penicillin. The loss of isotope at C2 oc...
Bewaard in:
| Gepubliceerd in: | Antimicrob Agents Chemother |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1975
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/809001/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.1.15 |
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