Pretargeted Imaging and Radioimmunotherapy of Cancer Using Antibodies and Bioorthogonal Chemistry

Selective delivery of radionuclides to tumors may be accomplished using a two-step approach, in which in the first step the tumor is pretargeted with an unlabeled antibody construct and in the second step the tumor is targeted with a radiolabeled small molecule. This results in a more rapid clearanc...

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Bibliographische Detailangaben
Veröffentlicht in:Front Med (Lausanne)
Hauptverfasser: van de Watering, Floor C. J., Rijpkema, Mark, Robillard, Marc, Oyen, Wim J. G., Boerman, Otto C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292049/
https://ncbi.nlm.nih.gov/pubmed/25593917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2014.00044
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