Pretargeted Imaging and Radioimmunotherapy of Cancer Using Antibodies and Bioorthogonal Chemistry

Selective delivery of radionuclides to tumors may be accomplished using a two-step approach, in which in the first step the tumor is pretargeted with an unlabeled antibody construct and in the second step the tumor is targeted with a radiolabeled small molecule. This results in a more rapid clearanc...

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Detalles Bibliográficos
Publicado en:Front Med (Lausanne)
Autores principales: van de Watering, Floor C. J., Rijpkema, Mark, Robillard, Marc, Oyen, Wim J. G., Boerman, Otto C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292049/
https://ncbi.nlm.nih.gov/pubmed/25593917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2014.00044
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