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Stochastic component to development of class I major histocompatibility complex-specific T cells.

The mechanism by which an initially uncommitted cell chooses between alternative fates is a central issue in developmental biology. In the mammalian thymus, CD4 helper T cells and CD8 cytotoxic T cells arise from a common precursor that expresses both CD4 and CD8. The choice between the CD4 and CD8...

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Détails bibliographiques
Auteurs principaux: Itano, A, Kioussis, D, Robey, E
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC42918/
https://ncbi.nlm.nih.gov/pubmed/7904067
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