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Stochastic component to development of class I major histocompatibility complex-specific T cells.

The mechanism by which an initially uncommitted cell chooses between alternative fates is a central issue in developmental biology. In the mammalian thymus, CD4 helper T cells and CD8 cytotoxic T cells arise from a common precursor that expresses both CD4 and CD8. The choice between the CD4 and CD8...

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Dettagli Bibliografici
Autori principali: Itano, A, Kioussis, D, Robey, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC42918/
https://ncbi.nlm.nih.gov/pubmed/7904067
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