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Effect of Protein Concentration and Binding on Antibiotic Assays

Assay curves, using a disk diffusion method for the antibiotics gentamicin and cefazolin, were prepared with: saline, saline plus 10% serum, and ascitic, synovial, cerebrospinal, and pleural fluids. The curves were compared with a standard curve prepared with pooled human serum. The pH, total protei...

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Bibliographic Details
Main Authors: Peterson, Lance R., Schierl, Elizabeth A., Hall, Wendell H.
Format: Artigo
Language:Inglês
Published: 1975
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC429179/
https://ncbi.nlm.nih.gov/pubmed/1096804
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