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Ascitic Fluid Cephalosporin Concentrations: Influence of Protein Binding and Serum Pharmacokinetics

Mongrel dogs with ascites created by inferior vena cava ligation were given cephalothin, cephaloridine, cefazolin, and cefamandole to evaluate the effect of protein binding and serum pharmacokinetics on the distribution of cephalosporins into ascitic fluid. Antibiotics were given intramuscularly (15...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Gerding, Dale N., Peterson, Lance R., Legler, Dwight C., Hall, Wendell H., Schierl, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1978
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/697350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.2.234
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