Hyper-Inflammation and Skin Destruction Mediated by Rosiglitazone Activation of Macrophages in IL-6 Deficiency

Injury initiates recruitment of macrophages to support tissue repair; however, excessive macrophage activity may exacerbate tissue damage causing further destruction and subsequent delay in wound repair. Here we show that the peroxisome proliferation–activated receptor-γ agonist, rosiglitazone (Rosi...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Das, Lopa M, Rosenjack, Julie, Au, Liemin, Galle, Pia S, Hansen, Morten B, Cathcart, Martha K, McCormick, Thomas S, Cooper, Kevin D, Silverstein, Roy L, Lu, Kurt Q
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291681/
https://ncbi.nlm.nih.gov/pubmed/25184961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.375
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