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Activation of Rab8 guanine nucleotide exchange factor Rabin8 by ERK1/2 in response to EGF signaling

Exocytosis is tightly regulated in many cellular processes, from neurite expansion to tumor proliferation. Rab8, a member of the Rab family of small GTPases, plays an important role in membrane trafficking from the trans-Golgi network and recycling endosomes to the plasma membrane. Rabin8 is a guani...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Wang, Juanfei, Ren, Jinqi, Wu, Bin, Feng, Shanshan, Cai, Guoping, Tuluc, Florin, Peränen, Johan, Guo, Wei
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291672/
https://ncbi.nlm.nih.gov/pubmed/25535387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412089112
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