γδ T cells affect IL-4 production and B-cell tolerance

γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells. One strain with a partial γδ deficiency that increase...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Huang, Yafei, Heiser, Ryan A., Detanico, Thiago O., Getahun, Andrew, Kirchenbaum, Greg A., Casper, Tamara L., Aydintug, M. Kemal, Carding, Simon R., Ikuta, Koichi, Huang, Hua, Cambier, John C., Wysocki, Lawrence J., O’Brien, Rebecca L., Born, Willi K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291655/
https://ncbi.nlm.nih.gov/pubmed/25535377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415107111
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