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γδ T cells affect IL-4 production and B-cell tolerance

γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells. One strain with a partial γδ deficiency that increase...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Huang, Yafei, Heiser, Ryan A., Detanico, Thiago O., Getahun, Andrew, Kirchenbaum, Greg A., Casper, Tamara L., Aydintug, M. Kemal, Carding, Simon R., Ikuta, Koichi, Huang, Hua, Cambier, John C., Wysocki, Lawrence J., O’Brien, Rebecca L., Born, Willi K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291655/
https://ncbi.nlm.nih.gov/pubmed/25535377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415107111
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