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Activity-dependent inhibitory synapse remodeling through gephyrin phosphorylation

Maintaining a proper balance between excitation and inhibition is essential for the functioning of neuronal networks. However, little is known about the mechanisms through which excitatory activity can affect inhibitory synapse plasticity. Here we used tagged gephyrin, one of the main scaffolding pr...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Flores, Carmen E., Nikonenko, Irina, Mendez, Pablo, Fritschy, Jean-Marc, Tyagarajan, Shiva K., Muller, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291629/
https://ncbi.nlm.nih.gov/pubmed/25535349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411170112
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