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Macrophage Elastase Suppresses White Adipose Tissue Expansion with Cigarette Smoking

Macrophage elastase (MMP12) is a key mediator of cigarette smoke (CS)-induced emphysema, yet its role in other smoking related pathologies remains unclear. The weight suppressing effects of smoking are a major hindrance to cessation efforts, and MMP12 is known to suppress the vascularization on whic...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Tsuji, Takao, Kelly, Neil J., Takahashi, Saeko, Leme, Adriana S., McGarry Houghton, A., Shapiro, Steven D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291548/
https://ncbi.nlm.nih.gov/pubmed/24914890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0083OC
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