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The Crossroads of Iron with Hypoxia and Cellular Metabolism. Implications in the Pathobiology of Pulmonary Hypertension

The pathologic hallmark of pulmonary arterial hypertension (PAH) is pulmonary vascular remodeling, characterized by endothelial cell proliferation, smooth muscle hypertrophy, and perivascular inflammation, ultimately contributing to increased pulmonary arterial pressures. Several recent studies have...

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Pubblicato in:Am J Respir Cell Mol Biol
Autori principali: Robinson, Jeffrey C., Graham, Brian B., Rouault, Tracey C., Tuder, Rubin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291546/
https://ncbi.nlm.nih.gov/pubmed/24988529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0021TR
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