The Crossroads of Iron with Hypoxia and Cellular Metabolism. Implications in the Pathobiology of Pulmonary Hypertension

The pathologic hallmark of pulmonary arterial hypertension (PAH) is pulmonary vascular remodeling, characterized by endothelial cell proliferation, smooth muscle hypertrophy, and perivascular inflammation, ultimately contributing to increased pulmonary arterial pressures. Several recent studies have...

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Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: Robinson, Jeffrey C., Graham, Brian B., Rouault, Tracey C., Tuder, Rubin M.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2014
Subjects:
Translational Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291546/
https://ncbi.nlm.nih.gov/pubmed/24988529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0021TR
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