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The Crossroads of Iron with Hypoxia and Cellular Metabolism. Implications in the Pathobiology of Pulmonary Hypertension

The pathologic hallmark of pulmonary arterial hypertension (PAH) is pulmonary vascular remodeling, characterized by endothelial cell proliferation, smooth muscle hypertrophy, and perivascular inflammation, ultimately contributing to increased pulmonary arterial pressures. Several recent studies have...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Robinson, Jeffrey C., Graham, Brian B., Rouault, Tracey C., Tuder, Rubin M.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291546/
https://ncbi.nlm.nih.gov/pubmed/24988529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0021TR
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