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Escaping the endoplasmic reticulum: why does a molecular chaperone leave home for greener pastures?

Molecular chaperones reside in nearly every organelle within a eukaryotic cell, and in each of these compartments, they ensure that protein homeostasis (or proteostasis) is maintained. In this issue, Wiseman and colleagues find that an ER lumenal chaperone escapes this compartment when a specific st...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Buck, Teresa M, Brodsky, Jeffrey L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291476/
https://ncbi.nlm.nih.gov/pubmed/25425576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490462
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