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Escaping the endoplasmic reticulum: why does a molecular chaperone leave home for greener pastures?

Molecular chaperones reside in nearly every organelle within a eukaryotic cell, and in each of these compartments, they ensure that protein homeostasis (or proteostasis) is maintained. In this issue, Wiseman and colleagues find that an ER lumenal chaperone escapes this compartment when a specific st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Buck, Teresa M, Brodsky, Jeffrey L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291476/
https://ncbi.nlm.nih.gov/pubmed/25425576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490462
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