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Escaping the endoplasmic reticulum: why does a molecular chaperone leave home for greener pastures?

Molecular chaperones reside in nearly every organelle within a eukaryotic cell, and in each of these compartments, they ensure that protein homeostasis (or proteostasis) is maintained. In this issue, Wiseman and colleagues find that an ER lumenal chaperone escapes this compartment when a specific st...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Buck, Teresa M, Brodsky, Jeffrey L
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291476/
https://ncbi.nlm.nih.gov/pubmed/25425576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490462
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