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Clostridium difficile Isolates with High Linezolid MICs Harbor the Multiresistance Gene cfr

We studied the molecular mechanisms of linezolid resistance in 9 isolates of toxigenic Clostridium difficile with high linezolid MICs. The activity of linezolid was determined against 891 clinical isolates of toxigenic C. difficile. The MIC(50) and MIC(90) of linezolid were 0.75 μg/ml and 1.5 μg/ml,...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Marín, Mercedes, Martín, Adoración, Alcalá, Luis, Cercenado, Emilia, Iglesias, Cristina, Reigadas, Elena, Bouza, Emilio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291439/
https://ncbi.nlm.nih.gov/pubmed/25385106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04082-14
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