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Clostridium difficile Isolates with High Linezolid MICs Harbor the Multiresistance Gene cfr

We studied the molecular mechanisms of linezolid resistance in 9 isolates of toxigenic Clostridium difficile with high linezolid MICs. The activity of linezolid was determined against 891 clinical isolates of toxigenic C. difficile. The MIC(50) and MIC(90) of linezolid were 0.75 μg/ml and 1.5 μg/ml,...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Marín, Mercedes, Martín, Adoración, Alcalá, Luis, Cercenado, Emilia, Iglesias, Cristina, Reigadas, Elena, Bouza, Emilio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291439/
https://ncbi.nlm.nih.gov/pubmed/25385106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04082-14
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