Cationic Liposomal Sodium Stibogluconate (SSG), a Potent Therapeutic Tool for Treatment of Infection by SSG-Sensitive and -Resistant Leishmania donovani

Pentavalent antimonials have been the first-line treatment for leishmaniasis for decades. However, the development of resistance to sodium stibogluconate (SSG) has limited its use, especially for treating visceral leishmaniasis (VL). The present work aims to optimize a cationic liposomal formulation...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Sinha, Roma, Roychoudhury, Jayeeta, Palit, Partha, Ali, Nahid
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291371/
https://ncbi.nlm.nih.gov/pubmed/25367907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03305-14
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