Effects of Divalent Cations on Binding of Aminoglycoside Antibiotics to Human Serum Proteins and to Bacteria

Binding of gentamicin and related deoxystreptamine-containing aminoglycoside antibiotics to proteins in human serum can vary significantly with changes in experimental conditions. The concentrations of divalent cations are important variables, and binding increases progressively as the concentration...

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Bibliographic Details
Main Authors: Ramirez-Ronda, Carlos H., Holmes, Randall K., Sanford, Jay P.
Format: Artigo
Language:Inglês
Published: 1975
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC429118/
https://ncbi.nlm.nih.gov/pubmed/1137375
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