Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance

Response to breast cancer chemoprevention can depend upon host genetic makeup and initiating events leading up to preneoplasia. Increased expression of aromatase and estrogen receptor (ER) is found in conjunction with breast cancer. To investigate response or resistance to endocrine therapy, mice wi...

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Veröffentlicht in:Carcinogenesis
Hauptverfasser: Dabydeen, Sarah A., Kang, Keunsoo, Díaz-Cruz, Edgar S., Alamri, Ahmad, Axelrod, Margaret L., Bouker, Kerrie B., Al-Kharboosh, Rawan, Clarke, Robert, Hennighausen, Lothar, Furth, Priscilla A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291054/
https://ncbi.nlm.nih.gov/pubmed/25421723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu237
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