Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance

Response to breast cancer chemoprevention can depend upon host genetic makeup and initiating events leading up to preneoplasia. Increased expression of aromatase and estrogen receptor (ER) is found in conjunction with breast cancer. To investigate response or resistance to endocrine therapy, mice wi...

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Publicado en:Carcinogenesis
Autores principales: Dabydeen, Sarah A., Kang, Keunsoo, Díaz-Cruz, Edgar S., Alamri, Ahmad, Axelrod, Margaret L., Bouker, Kerrie B., Al-Kharboosh, Rawan, Clarke, Robert, Hennighausen, Lothar, Furth, Priscilla A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291054/
https://ncbi.nlm.nih.gov/pubmed/25421723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu237
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