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Responsiveness of Brca1 and Trp53 deficiency induced mammary preneoplasia to selective estrogen modulators versus an aromatase inhibitor in Mus musculus

An intervention study initiated at age 4 months compared the impact of tamoxifen (25mg), raloxifene (22.5mg) and letrozole (2.5mg) administered by 60-day-release-subcutaneous-pellet on mammary preneoplasia prevalence at age 6 months in conditional genetically engineered mouse models with different B...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Alothman, Sahar J., Wang, Weisheng, Goerlitz, David S., Islam, Md, Zhong, Xiaogang, Kishore, Archana, Azhar, Redha I., Kallakury, Bhaskar V., Furth, Priscilla A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466868/
https://ncbi.nlm.nih.gov/pubmed/28283467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0268
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