CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers—findings from two independent populations

We investigated genetic variation in CYP2A6 in relation to lung cancer risk among African American smokers, a high-risk population. Previously, we found that CYP2A6, a nicotine/nitrosamine metabolism gene, was associated with lung cancer risk in European Americans, but smoking habits, lung cancer ri...

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Publicado en:Carcinogenesis
Main Authors: Wassenaar, Catherine A., Ye, Yuanqing, Cai, Qiuyin, Aldrich, Melinda C., Knight, Joanne, Spitz, Margaret R., Wu, Xifeng, Blot, William J., Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291053/
https://ncbi.nlm.nih.gov/pubmed/25416559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu235
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