CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers—findings from two independent populations

We investigated genetic variation in CYP2A6 in relation to lung cancer risk among African American smokers, a high-risk population. Previously, we found that CYP2A6, a nicotine/nitrosamine metabolism gene, was associated with lung cancer risk in European Americans, but smoking habits, lung cancer ri...

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發表在:Carcinogenesis
Main Authors: Wassenaar, Catherine A., Ye, Yuanqing, Cai, Qiuyin, Aldrich, Melinda C., Knight, Joanne, Spitz, Margaret R., Wu, Xifeng, Blot, William J., Tyndale, Rachel F.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291053/
https://ncbi.nlm.nih.gov/pubmed/25416559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu235
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