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Isolation and Characterization of a γ-Thiochromanone-4-Thiosemicarbazone-Resistant Mutant of Vaccinia Virus

γ-Thiochromanone-4-thiosemicarbazone (TCT) inhibits the growth of vaccinia virus in BSCl cells by interfering with viral maturation. A mutant of the virus (TCT(R)) which is resistant to this drug was isolated. This mutant also exhibits resistance to another thiosemicarbazone related compound, isatin...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Katz, Ehud, Margalith, Eva, Winer, Bela
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1975
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1137362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.7.1.85
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