Compound A, a selective glucocorticoid receptor agonist, inhibits immunoinflammatory diabetes, induced by multiple low doses of streptozotocin in mice

BACKGROUND AND PURPOSE: Type 1 diabetes is a multifactorial inflammatory disease that develops as a result of deregulated immune responses, causing progressive autoimmune destruction of insulin-producing beta cells of pancreas. 2-((4-acetoxyphenyl)-2-chloro-N-methyl) ethylammonium chloride, compound...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Saksida, T, Vujicic, M, Nikolic, I, Stojanovic, I, Haegeman, G, Stosic-Grujicic, S
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290725/
https://ncbi.nlm.nih.gov/pubmed/25158597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12892
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