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Leflunomide protects mice from multiple low dose streptozotocin (MLD-SZ)-induced insulitis and diabetes

In certain animal models of autoimmunity the isoxasol derivative leflunomide has been reported to exert a protective effect against autodestruction. In the present study, the immunomodulatory potential of the main metabolite of leflunomide, A77 1726, in experimentally induced autoimmune diabetes was...

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Hlavní autoři: STOSIC-GRUJICIC, S, DIMITRIJEVIC, M, BARTLETT, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905462/
https://ncbi.nlm.nih.gov/pubmed/10403914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00900.x
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