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PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling
BACKGROUND AND PURPOSE: Angiogenesis contributes to coronary heart disease, immune disorders and numerous malignancies. VEGF-A and its receptors (VEGFRs) play a pivotal role in regulating angiogenesis. In an effort to discover more effective inhibitors of tumour angiogenesis, we have analysed the ac...
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| Udgivet i: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4290713/ https://ncbi.nlm.nih.gov/pubmed/25091695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12872 |
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