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PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling

BACKGROUND AND PURPOSE: Angiogenesis contributes to coronary heart disease, immune disorders and numerous malignancies. VEGF-A and its receptors (VEGFRs) play a pivotal role in regulating angiogenesis. In an effort to discover more effective inhibitors of tumour angiogenesis, we have analysed the ac...

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Bibliografische gegevens
Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: Huang, S W, Lien, J C, Kuo, S C, Huang, T F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290713/
https://ncbi.nlm.nih.gov/pubmed/25091695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12872
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