Selective Na(+)/Ca2(+) exchanger inhibition prevents Ca2(+) overload-induced triggered arrhythmias

BACKGROUND AND PURPOSE: Augmented Na(+)/Ca(2+) exchanger (NCX) activity may play a crucial role in cardiac arrhythmogenesis; however, data regarding the anti-arrhythmic efficacy of NCX inhibition are debatable. Feasible explanations could be the unsatisfactory selectivity of NCX inhibitors and/or th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Nagy, Norbert, Kormos, Anita, Kohajda, Zsófia, Szebeni, Áron, Szepesi, Judit, Pollesello, Piero, Levijoki, Jouko, Acsai, Károly, Virág, László, Nánási, Péter P, Papp, Julius Gy, Varró, András, Tóth, András
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290709/
https://ncbi.nlm.nih.gov/pubmed/25073832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12867
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