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A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases

The universal second messenger cAMP is generated upon stimulation of G(s) protein-coupled receptors, such as the β(2)-adreneoceptor, and leads to the activation of PKA, the major cAMP effector protein. PKA oscillates between an on and off state and thereby regulates a plethora of distinct biological...

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Publicat a:Br J Pharmacol
Autors principals: Poppinga, W J, Muñoz-Llancao, P, González-Billault, C, Schmidt, M
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290705/
https://ncbi.nlm.nih.gov/pubmed/25132049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12882
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